John Hart Selected Research

INCB3619

1/2017

ADAM17 is a Tumor Promoter and Therapeutic Target in Western Diet-associated Colon Cancer.

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John Hart Research Topics

Disease

51	Neoplasms (Cancer) 11/2022 - 10/2002
23	Colonic Neoplasms (Colon Cancer) 12/2021 - 10/2002
22	Carcinogenesis 12/2021 - 12/2002
14	Adenocarcinoma 11/2022 - 10/2002
11	Inflammation (Inflammations) 01/2022 - 01/2009
9	Fibrosis (Cirrhosis) 01/2020 - 03/2003
7	Ulcerative Colitis 01/2022 - 01/2002
7	Trachoma 06/2021 - 07/2014
7	Colitis 01/2019 - 10/2007
7	Colorectal Neoplasms (Colorectal Cancer) 01/2019 - 10/2002
6	Traumatic Brain Injuries (Traumatic Brain Injury) 03/2022 - 01/2017
6	Adenoma (Adenomas) 01/2020 - 10/2002
6	Hepatocellular Carcinoma (Hepatoma) 01/2020 - 04/2006
5	Cognitive Dysfunction 06/2022 - 01/2017
5	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/2022 - 01/2006
5	Infections 01/2021 - 08/2007
5	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2019 - 09/2004
5	Carcinoma (Carcinomatosis) 03/2016 - 01/2002
5	Aberrant Crypt Foci 04/2008 - 12/2002
4	Multiple Sclerosis 06/2022 - 09/2007
4	Hemorrhage 11/2019 - 07/2009
4	Necrosis 06/2016 - 08/2008
3	Barrett Esophagus (Barrett's Esophagus) 11/2022 - 04/2005
3	Alzheimer Disease (Alzheimer's Disease) 06/2022 - 01/2017
3	Dementia (Dementias) 06/2022 - 01/2019
3	Wounds and Injuries (Trauma) 01/2022 - 07/2013
3	Autoimmune Hepatitis 02/2020 - 08/2006
3	Neoplasm Metastasis (Metastasis) 01/2018 - 04/2006
3	Neoplasms, Cystic, Mucinous, and Serous 01/2016 - 08/2002
3	Gastritis 01/2013 - 02/2004
3	Hepatic Veno-Occlusive Disease (Disease, Hepatic Veno-Occlusive) 08/2012 - 09/2004
3	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 01/2009 - 10/2002
3	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 05/2008 - 07/2003
2	Atrophy 08/2022 - 08/2012
2	Unconsciousness (Loss of Consciousness) 01/2021 - 01/2017
2	Hepatitis 02/2020 - 03/2008
2	Body Weight (Weight, Body) 04/2018 - 01/2007
2	Mental Disorders (Mental Disorder) 01/2018 - 01/2011
2	Anus Neoplasms (Anal Cancer) 01/2018 - 01/2018
2	Fatigue 11/2017 - 01/2017
2	Disease Progression 01/2017 - 04/2005
2	Pain (Aches) 01/2017 - 03/2008
2	Crohn Disease (Crohn's Disease) 03/2016 - 09/2004
2	Acute Liver Failure (Fulminant Hepatic Failure) 01/2016 - 08/2003
2	Non-alcoholic Fatty Liver Disease 11/2015 - 10/2013

Drug/Important Bio-Agent (IBA)

17	AzoxymethaneIBA 11/2019 - 11/2002
12	Proteins (Proteins, Gene)FDA Link 03/2021 - 10/2002
8	beta CateninIBA 10/2012 - 10/2002
7	ErbB Receptors (EGF Receptor)IBA 01/2017 - 07/2003
7	Dextran SulfateIBA 01/2015 - 10/2007
6	MicroRNAs (MicroRNA)IBA 12/2021 - 07/2011
6	AntibodiesIBA 11/2021 - 04/2006
6	Azithromycin (Zithromax)FDA LinkGeneric 06/2021 - 07/2014
6	Epidermal Growth Factor (EGF)IBA 01/2017 - 01/2007
6	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 10/2012 - 12/2002
6	Cyclin D1IBA 10/2012 - 10/2002
5	Biomarkers (Surrogate Marker)IBA 06/2022 - 12/2002
5	Messenger RNA (mRNA)IBA 01/2017 - 10/2002
4	Oxygen (Dioxygen)IBA 11/2017 - 04/2010
4	Formaldehyde (Formol)FDA Link 01/2014 - 12/2002
4	Cadherins (E-Cadherin)IBA 08/2009 - 12/2002
3	salicylhydroxamic acid (SHAM)IBA 01/2022 - 01/2017
3	Amyloid (Amyloid Fibrils)IBA 01/2022 - 01/2019
3	Transcription Factors (Transcription Factor)IBA 11/2019 - 07/2005
3	CarcinogensIBA 11/2019 - 11/2002
3	ReninIBA 01/2019 - 11/2014
3	Losartan (Cozaar)FDA LinkGeneric 01/2019 - 01/2016
3	Vitamin D FDA LinkGeneric 01/2019 - 10/2007
3	Hormones (Hormone)IBA 08/2016 - 09/2004
3	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2009 - 12/2002
3	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 07/2003 - 11/2002
2	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 08/2009
2	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 01/2022 - 03/2018
2	LuciferasesIBA 12/2021 - 01/2017
2	TESIBA 01/2021 - 01/2017
2	AntigensIBA 01/2021 - 12/2008
2	MucinsIBA 03/2020 - 01/2016
2	pembrolizumabIBA 02/2020 - 01/2020
2	NivolumabIBA 02/2020 - 01/2020
2	Trastuzumab (Herceptin)FDA Link 01/2020 - 10/2016
2	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 04/2005
2	RNA (Ribonucleic Acid)IBA 04/2018 - 08/2017
2	3' Untranslated Regions (3' UTR)IBA 09/2017 - 01/2017
2	CateninsIBA 01/2017 - 11/2014
2	Angiotensin IIIBA 01/2016 - 11/2014
2	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 01/2016 - 01/2009
2	Alanine Transaminase (SGPT)IBA 11/2015 - 10/2013

Therapy/Procedure

25	Therapeutics 01/2022 - 01/2002
9	Transcranial Direct Current Stimulation 08/2022 - 01/2017
6	Mass Drug Administration 06/2021 - 08/2014
6	Liver Transplantation 08/2017 - 07/2003
4	Transcranial Magnetic Stimulation 01/2022 - 01/2011
4	Colectomy 01/2022 - 01/2013
4	Lasers (Laser) 07/2017 - 01/2011
3	Esophagectomy 11/2022 - 04/2005
3	Restorative Proctocolectomy 01/2022 - 03/2016
3	Chemoprevention 01/2019 - 01/2005
2	Drug Therapy (Chemotherapy) 01/2018 - 01/2018
2	Radiotherapy 01/2018 - 01/2018
2	Transplantation 08/2017 - 05/2003